The Enzyme Database

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Accepted name: neoxanthin synthase
Reaction: violaxanthin = neoxanthin
For diagram of the biosynthesis of capsanthin, capsarubin and neoxanthin, click here and for diagram of carotenoid epoxide rearrangements, click here
Other name(s): NSY
Systematic name: violaxanthin—neoxanthin isomerase (epoxide-opening)
Comments: The opening of the epoxide ring of violaxanthin generates a chiral allene. Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants [2].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 318960-21-3
1.  Al-Babili, S., Hugueney, P., Schledz, M., Welsch, R., Frohnmeyer, H., Laule, O. and Beyer, P. Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum. FEBS Lett. 485 (2000) 168–172. [DOI] [PMID: 11094161]
2.  Bouvier, F., d'Harlingue, A., Backhaus, R.A., Kumagai, M.H. and Camara, B. Identification of neoxanthin synthase as a carotenoid cyclase paralog. Eur. J. Biochem. 267 (2000) 6346–6352. [DOI] [PMID: 11029576]
[EC created 2005]

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