| EC |
5.4.2.9 |
| Accepted name: |
phosphoenolpyruvate mutase |
| Reaction: |
phosphoenolpyruvate = 3-phosphonopyruvate |
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For diagram of reaction, click here |
| Other name(s): |
phosphoenolpyruvate-phosphonopyruvate phosphomutase; PEP phosphomutase; phosphoenolpyruvate phosphomutase; PEPPM; PEP phosphomutase |
| Systematic name: |
phosphoenolpyruvate 2,3-phosphonomutase |
| Comments: |
Involved in the biosynthesis of the C-P bond, although the equilibrium greatly favours phosphoenolpyruvate. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 115756-49-5 |
| References: |
| 1. |
Bowman, E., McQueney, M., Barry, R.J. and Dunaway-Mariano, D. Catalysis and thermodynamics of the phosphoenolpyruvate phosphonopyruvate rearrangement - entry into the phosphonate class of naturally-occurring organo-phosphorus compounds. J. Am. Chem. Soc. 110 (1988) 5575–5576. |
| 2. |
Hikada, T., Imai, S., Hara, O., Anzai, H., Murakami, T., Nagaoka, K. and Seto, H. Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation. J. Bacteriol. 172 (1990) 3066–3072. [DOI] [PMID: 2160937] |
| 3. |
Seidel, H.M., Freeman, S. and Knowles, J.R. Phosphonate biosynthesis: isolation of the enzyme responsible for the formation of a carbon-phosphorus bond. Nature 335 (1988) 457–458. [DOI] [PMID: 3138545] |
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| [EC 5.4.2.9 created 1990] |
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