ExplorEnz: EC 5.4.3.7

EC

5.4.3.7

Accepted name:

leucine 2,3-aminomutase

Reaction:

(2S)-α-leucine = (3R)-β-leucine

Systematic name:

(2S)-α-leucine 2,3-aminomutase

Comments:

Requires a cobamide cofactor.

References:

1.	Freer, I., Pedrocchi-Fantoni, G., Picken, D.J. and Overton, K.H. Stereochemistry of the leucine 2,3-aminomutase from tissue-cultures of Andrographis paniculata. J. Chem. Soc. Chem. Commun. (1981) 80–82.
2.	Poston, J.M. Leucine 2,3-aminomutase, an enzyme of leucine catabolism. J. Biol. Chem. 251 (1976) 1859–1863. [PMID: 1270414]
3.	Poston, J.M. Coenzyme B₁₂-dependent enzymes in potatoes: leucine 2,3-aminomutase and methylmalonyl-CoA mutase. Phytochemistry 17 (1978) 401–402.

[EC 5.4.3.7 created 1982]