The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: 23S rRNA pseudouridine2604 synthase
Reaction: 23S rRNA uridine2604 = 23S rRNA pseudouridine2604
Other name(s): RluF; YjbC
Systematic name: 23S rRNA-uridine2604 uracil mutase
Comments: The enzyme is not completely specific for uridine2604 and can, to a small extent, also react with uridine2605 [1].
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB
1.  Del Campo, M., Kaya, Y. and Ofengand, J. Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. RNA 7 (2001) 1603–1615. [PMID: 11720289]
2.  Alian, A., DeGiovanni, A., Griner, S.L., Finer-Moore, J.S. and Stroud, R.M. Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome. J. Mol. Biol. 388 (2009) 785–800. [DOI] [PMID: 19298824]
3.  Sunita, S., Zhenxing, H., Swaathi, J., Cygler, M., Matte, A. and Sivaraman, J. Domain organization and crystal structure of the catalytic domain of E. coli RluF, a pseudouridine synthase that acts on 23S rRNA. J. Mol. Biol. 359 (2006) 998–1009. [DOI] [PMID: 16712869]
[EC created 2011]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald