EC |
5.4.99.50 |
Accepted name: |
friedelin synthase |
Reaction: |
(3S)-2,3-epoxy-2,3-dihydrosqualene = friedelin |
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For diagram of friedelin, glutinol, isomultiflorenol and taraxerol biosynthesis, click here |
Systematic name: |
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, friedelin-forming) |
Comments: |
The enzyme from Kalanchoe daigremontiana also gives traces of other triterpenoids. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Wang, Z., Yeats, T., Han, H. and Jetter, R. Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids. J. Biol. Chem. 285 (2010) 29703–29712. [DOI] [PMID: 20610397] |
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[EC 5.4.99.50 created 2011] |
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