EC |
5.4.99.56 |
Accepted name: |
tirucalladienol synthase |
Reaction: |
(3S)-2,3-epoxy-2,3-dihydrosqualene = tirucalla-7,24-dien-3β-ol |
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For diagram of dammarenediol II and tirucalla-7,24-dien-3β-ol biosynthesis, click here |
Other name(s): |
PEN3 |
Systematic name: |
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, tirucalla-7,24-dien-3β-ol-forming) |
Comments: |
The product from Arabidopsis thaliana is 85% tirucalla-7,24-dien-3β-ol with trace amounts of other triterpenoids. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Morlacchi, P., Wilson, W.K., Xiong, Q., Bhaduri, A., Sttivend, D., Kolesnikova, M.D. and Matsuda, S.P. Product profile of PEN3: the last unexamined oxidosqualene cyclase in Arabidopsis thaliana. Org. Lett. 11 (2009) 2627–2630. [DOI] [PMID: 19445469] |
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[EC 5.4.99.56 created 2011] |
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