| EC |
5.4.99.63 |
| Accepted name: |
ethylmalonyl-CoA mutase |
| Reaction: |
(2R)-ethylmalonyl-CoA = (2S)-methylsuccinyl-CoA |
| Other name(s): |
Ecm |
| Systematic name: |
(2R)-ethylmalonyl-CoA CoA-carbonylmutase |
| Comments: |
The enzyme, characterized from the bacterium Rhodobacter sphaeroides, is involved in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation. Requires adenosylcobalamin for activity. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Erb, T.J., Retey, J., Fuchs, G. and Alber, B.E. Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases. J. Biol. Chem. 283 (2008) 32283–32293. [DOI] [PMID: 18819910] |
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| [EC 5.4.99.63 created 2015] |
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