| EC |
5.5.1.17 |
| Accepted name: |
(S)-β-macrocarpene synthase |
| Reaction: |
(S)-β-bisabolene = (S)-β-macrocarpene |
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For diagram of biosynthesis of bicyclic sesquiterpenoids derived from bisabolyl cation, click here and for diagram of bisabolene and macrocarpene biosynthesis, click here |
| Other name(s): |
TPS6; TPS11; (S)-β-macrocarpene lyase (decyclizing) |
| Systematic name: |
(S)-β-macrocarpene lyase (ring-opening) |
| Comments: |
The synthesis of (S)-β-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps. The first step is the cyclization to (S)-β-bisabolene (cf. EC 4.2.3.55, (S)-β-bisabolene synthase). The second step is the isomerization to (S)-β-macrocarpene. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Kollner, T.G., Schnee, C., Li, S., Svatos, A., Schneider, B., Gershenzon, J. and Degenhardt, J. Protonation of a neutral (S)-β-bisabolene intermediate is involved in (S)-β-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11. J. Biol. Chem. 283 (2008) 20779–20788. [DOI] [PMID: 18524777] |
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| [EC 5.5.1.17 created 2011] |
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