| EC |
6.2.1.1 |
| Accepted name: |
acetate—CoA ligase |
| Reaction: |
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA |
| Other name(s): |
acetyl-CoA synthetase; acetyl activating enzyme; acetate thiokinase; acyl-activating enzyme; acetyl coenzyme A synthetase; acetic thiokinase; acetyl CoA ligase; acetyl CoA synthase; acetyl-coenzyme A synthase; short chain fatty acyl-CoA synthetase; short-chain acyl-coenzyme A synthetase; ACS |
| Systematic name: |
acetate:CoA ligase (AMP-forming) |
| Comments: |
Also acts on propanoate and propenoate. |
| Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9012-31-1 |
| References: |
| 1. |
Chou, T.C. and Lipmann, F. Separation of acetyl transfer enzymes in pigeon liver extract. J. Biol. Chem. 196 (1952) 89–103. [PMID: 12980945] |
| 2. |
Eisenberg, M.A. The acetate-activating enzyme of Rhodospirillum rubrum. Biochim. Biophys. Acta 16 (1955) 58–65. [DOI] [PMID: 14363230] |
| 3. |
Hele, P. The acetate activating enzyme of beef heart. J. Biol. Chem. 206 (1954) 671–676. [PMID: 13143026] |
| 4. |
Millerd, A. and Bonner, J. Acetate activation and acetoacetate formation in plant systems. Arch. Biochem. Biophys. 49 (1954) 343–355. [DOI] [PMID: 13159282] |
|
| [EC 6.2.1.1 created 1961] |
| |
|
| |
|
Printable version