| EC |
6.2.1.13 |
| Accepted name: |
acetate—CoA ligase (ADP-forming) |
| Reaction: |
ATP + acetate + CoA = ADP + phosphate + acetyl-CoA |
| Other name(s): |
acetyl-CoA synthetase (ADP-forming); acetyl coenzyme A synthetase (adenosine diphosphate-forming); acetate thiokinase |
| Systematic name: |
acetate:CoA ligase (ADP-forming) |
| Comments: |
Also acts on propanoate and, very slowly, on butanoate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 62009-85-2 |
| References: |
| 1. |
Reeves, R.E., Warren, L.G., Susskind, B. and Lo, H.-S. An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. Pyruvate synthase and a new acetate thiokinase. J. Biol. Chem. 252 (1977) 726–731. [PMID: 13076] |
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| [EC 6.2.1.13 created 1978] |
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