| EC |
6.2.1.15 |
| Accepted name: |
arachidonate—CoA ligase |
| Reaction: |
ATP + arachidonate + CoA = AMP + diphosphate + arachidonoyl-CoA |
| Glossary: |
arachidonate = (all-Z)-icosa-5,8,11,14-tetraenoate |
| Other name(s): |
arachidonoyl-CoA synthetase |
| Systematic name: |
arachidonate:CoA ligase (AMP-forming) |
| Comments: |
Not identical with EC 6.2.1.3 long-chain-fatty-acid—CoA ligase. Icosa-8,11,14-trienoate, but not the other long-chain fatty acids, can act in place of arachidonate. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 82047-87-8 |
| References: |
| 1. |
Wilson, D.B., Prescott, S.M. and Majerus, P.W. Discovery of an arachidonoyl coenzyme A synthetase in human platelets. J. Biol. Chem. 257 (1982) 3510–3515. [PMID: 7061494] |
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| [EC 6.2.1.15 created 1984] |
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