| EC |
6.2.1.16 |
| Accepted name: |
acetoacetate—CoA ligase |
| Reaction: |
ATP + acetoacetate + CoA = AMP + diphosphate + acetoacetyl-CoA |
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For diagram of mevalonate biosynthesis, click here |
| Other name(s): |
acetoacetyl-CoA synthetase |
| Systematic name: |
acetoacetate:CoA ligase (AMP-forming) |
| Comments: |
Also acts, more slowly, on L-3-hydroxybutanoate. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 39394-62-2 |
| References: |
| 1. |
Fukui, T., Ito, M. and Tomita, K. Purification and characterization of acetoacetyl-CoA synthetase from Zoogloea ramigera I-16-M. Eur. J. Biochem. 127 (1982) 423–428. [DOI] [PMID: 7140777] |
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| [EC 6.2.1.16 created 1984] |
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