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Your query returned 1 entry. Printable version
EC | 6.2.1.49 | ||||||||||
Accepted name: | long-chain fatty acid adenylyltransferase FadD28 | ||||||||||
Reaction: | ATP + a long-chain fatty acid + holo-[mycocerosate synthase] = AMP + diphosphate + a long-chain acyl-[mycocerosate synthase] (overall reaction) (1a) ATP + a long-chain fatty acid = diphosphate + a long-chain acyl-adenylate ester (1b) a long-chain acyl-adenylate ester + holo-[mycocerosate synthase] = AMP + a long-chain acyl-[mycocerosate synthase] |
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Other name(s): | fadD28 (gene name) | ||||||||||
Systematic name: | long-chain fatty acid:holo-[mycocerosate synthase] ligase (AMP-forming) | ||||||||||
Comments: | The enzyme, found in certain mycobacteria, activates long-chain fatty acids by adenylation and transfers them to EC 2.3.1.111, mycocerosate synthase. The enzyme participates in the biosynthesis of the virulent lipids dimycocerosates (DIM) and dimycocerosyl triglycosyl phenolphthiocerol (PGL). | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||
References: |
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