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| EC | 6.3.2.44 | ||
| Accepted name: | pantoate—β-alanine ligase (ADP-forming) | ||
| Reaction: | ATP + (R)-pantoate + β-alanine = ADP + phosphate + (R)-pantothenate | ||
| For diagram of coenzyme A biosynthesis (early stages), click here | |||
| Glossary: | (R)-pantoate = (2R)-2,4-dihydroxy-3,3-dimethylbutanoate (R)-pantothenate = 3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanoate |
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| Other name(s): | pantothenate synthetase (ambiguous); pantoate—β-alanine ligase (ambiguous) | ||
| Systematic name: | (R)-pantoate:β-alanine ligase (ADP-forming) | ||
| Comments: | The enzyme, characterized from the archaeon Methanosarcina mazei, is involved in the biosynthesis of pantothenate. It is different from EC 6.3.2.1, the AMP-forming pantoate-β-alanine ligase found in bacteria and eukaryota. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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