| EC |
6.3.4.17 |
| Accepted name: |
formate—dihydrofolate ligase |
| Reaction: |
ATP + formate + dihydrofolate = ADP + phosphate + 10-formyldihydrofolate |
| Other name(s): |
formyltransferase, dihydrofolate; dihydrofolate formyltransferase; formyl dihydrofolate synthase |
| Systematic name: |
formate:dihydrofolate ligase (ADP-forming) |
| Comments: |
Not identical with EC 6.3.4.3 (formate—tetrahydrofolate ligase). |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 123303-25-3 |
| References: |
| 1. |
Drake, J.C., Baram, J. and Allegra, C.J. Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells. Biochem. Pharmacol. 39 (1990) 615–618. [DOI] [PMID: 2306274] |
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| [EC 6.3.4.17 created 1992] |
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