| EC |
7.2.2.17 |
| Accepted name: |
ABC-type ferric enterobactin transporter |
| Reaction: |
ATP + H2O + Fe3+-enterobactin complex-[enterobactin-binding protein][side 1] = ADP + phosphate + Fe3+-enterobactin complex[side 2] + [enterobactin-binding protein][side 1] |
| Other name(s): |
ferric enterobactin transporting ATPase; ferric enterobactin ABC transporter; fepBCDG (gene names) |
| Systematic name: |
ATP phosphohydrolase (ABC-type, iron(III) enterobactin-importing) |
| Comments: |
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of Fe3+-enterobactin complexes. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Chenault, S.S. and Earhart, C.F. Organization of genes encoding membrane proteins of the Escherichia coli ferrienterobactin permease. Mol. Microbiol. 5 (1991) 1405–1413. [PMID: 1787794] |
| 2. |
Shea, C.M. and McIntosh, M.A. Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding-protein-dependent systems in Escherichia coli. Mol. Microbiol. 5 (1991) 1415–1428. [DOI] [PMID: 1838574] |
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| [EC 7.2.2.17 created 2000 as EC 3.6.3.34, part transferred 2018 to EC 7.2.2.17] |
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