ExplorEnz: EC 7.6.2.16

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7.6.2.16

Accepted name:

ABC-type putrescine transporter

Reaction:

ATP + H₂O + putrescine-[putrescine-binding protein]_{[side 1]} = ADP + phosphate + putrescine_{[side 2]} + [putrescine-binding protein]_{[side 1]}

Other name(s):

putrescine transporting ATPase; putrescine ABC transporter; potFGHI (gene names)

Systematic name:

ATP phosphohydrolase (ABC-type, putrescine-importing)

Comments:

ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from the bacterium Escherichia coli interacts with an extracytoplasmic substrate binding protein and mediates the high affinity uptake of putrescine. Differs in specificity from EC 7.6.2.11, ABC-type polyamine transporter.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Pistocchi, R., Kashiwagi, K., Miyamoto, S., Nukui, E., Sadakata, Y., Kobayashi, H. and Igarashi, K. Characteristics of the operon for a putrescine transport system that maps at 19 minutes on the Escherichia coli chromosome. J. Biol. Chem. 268 (1993) 146–152. [PMID: 8416922]
2.	Terui, Y., Saroj, S.D., Sakamoto, A., Yoshida, T., Higashi, K., Kurihara, S., Suzuki, H., Toida, T., Kashiwagi, K. and Igarashi, K. Properties of putrescine uptake by PotFGHI and PuuP and their physiological significance in Escherichia coli. Amino Acids 46 (2014) 661–670. [PMID: 23719730]

[EC 7.6.2.16 created 2019]