| EC |
7.6.2.5 |
| Accepted name: |
ABC-type heme transporter |
| Reaction: |
ATP + H2O + heme[side 1] = ADP + phosphate + heme[side 2] |
| Other name(s): |
heme-transporting ATPase |
| Systematic name: |
ATP phosphohydrolase (ABC-type, heme-exporting) |
| Comments: |
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. Does not undergo phosphorylation during the transport process. The enzyme has been described from Gram-negative bacteria and green plants. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Ramseier, T.M., Winteler, H.V. and Hennecke, H. Discovery and sequence analysis of bacterial genes involved in the biogenesis of c-type cytochromes. J. Biol. Chem. 266 (1991) 7793–7803. [PMID: 1850420] |
| 2. |
Jekabsons, W. and Schuster, W. orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria. Mol. Gen. Genet. 246 (1995) 166–173. [PMID: 7862087] |
| 3. |
Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81–136. [PMID: 9889977] |
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| [EC 7.6.2.5 created 2000 as EC 3.6.3.41, transferred 2018 to EC 7.6.2.5] |
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