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Your query returned 4 entries. Printable version
EC | 2.8.3.22 | ||||||
Accepted name: | succinyl-CoA—L-malate CoA-transferase | ||||||
Reaction: | (1) succinyl-CoA + (S)-malate = succinate + (S)-malyl-CoA (2) succinyl-CoA + (S)-citramalate = succinate + (S)-citramalyl-CoA |
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For diagram of the 3-hydroxypropanoate cycle, click here | |||||||
Glossary: | (S)-citramalate = (2S)-2-hydroxy-2-methylbutanedioate (S)-malate = (2S)-2-hydroxybutanedioate (S)-malyl-CoA = (3S)-3-carboxy-3-hydroxypropanoyl-CoA |
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Other name(s): | SmtAB | ||||||
Systematic name: | succinyl-CoA:(S)-malate CoA-transferase | ||||||
Comments: | The enzyme, purified from the bacterium Chloroflexus aurantiacus, can also accept itaconate as acceptor, with lower efficiency. It is part of the 3-hydroxypropanoate cycle for carbon assimilation. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
References: |
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EC | 4.1.3.25 | ||||||
Accepted name: | (S)-citramalyl-CoA lyase | ||||||
Reaction: | (3S)-citramalyl-CoA = acetyl-CoA + pyruvate | ||||||
For diagram of the 3-hydroxypropanoate cycle, click here | |||||||
Other name(s): | citramalyl coenzyme A lyase (ambiguous); (+)-CMA-CoA lyase; (3S)-citramalyl-CoA pyruvate-lyase; Mcl (ambiguous); citramalyl-CoA lyase (ambiguous) | ||||||
Systematic name: | (3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming) | ||||||
Comments: | Requires Mg2+ ions for activity [3]. The enzyme from the bacterium Clostridium tetanomorphum is a component of EC 4.1.3.22, citramalate lyase [2]. It also acts on (3S)-citramalyl thioacyl-carrier protein [2]. The enzyme from the bacterium Chloroflexus aurantiacus also has the activity of EC 4.1.3.24, malyl-CoA lyase [3]. It has no activity with (3R)-citramalyl-CoA (cf. EC 4.1.3.46, (R)-citramalyl-CoA lyase) [3]. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37290-68-9 | ||||||
References: |
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EC | 4.1.3.46 | ||||||
Accepted name: | (R)-citramalyl-CoA lyase | ||||||
Reaction: | (3R)-citramalyl-CoA = acetyl-CoA + pyruvate | ||||||
Other name(s): | Ccl | ||||||
Systematic name: | (3R)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming) | ||||||
Comments: | Requires Mn2+ ions for activity. The enzyme, purified from the bacterium Chloroflexus aurantiacus, has no activity with (3S)-citramalyl-CoA (cf. EC 4.1.3.25, (S)-citramalyl-CoA lyase). | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
References: |
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EC | 4.2.1.153 | ||||||
Accepted name: | 3-methylfumaryl-CoA hydratase | ||||||
Reaction: | (S)-citramalyl-CoA = 3-methylfumaryl-CoA + H2O | ||||||
For diagram of the 3-hydroxypropanoate cycle, click here | |||||||
Glossary: | (S)-citramalyl-CoA = (3S)-3-carboxy-3-hydroxybutanoyl-CoA 3-methylfumaryl-CoA = (E)-3-carboxybut-2-enoyl-CoA |
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Other name(s): | Meh; mesaconyl-C4-CoA hydratase; mesaconyl-coenzyme A hydratase (ambiguous) | ||||||
Systematic name: | (S)-citramalyl-CoA hydro-lyase (3-methylfumaryl-CoA-forming) | ||||||
Comments: | The enzyme from the bacterium Chloroflexus aurantiacus is part of the 3-hydroxypropanoate cycle for carbon assimilation. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
References: |
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