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Your query returned 3 entries. 
Printable version
| EC | 2.7.1.203 | ||||||||
| Accepted name: | protein-Nπ-phosphohistidine—D-glucosaminate phosphotransferase | ||||||||
| Reaction: | [protein]-Nπ-phospho-L-histidine + 2-amino-2-deoxy-D-gluconate[side 1] = [protein]-L-histidine + 2-amino-2-deoxy-D-gluconate 6-phosphate[side 2] | ||||||||
| Other name(s): | dgaABCD (gene names); 2-amino-2-deoxy-D-gluconate PTS permease | ||||||||
| Systematic name: | protein-Nπ-phospho-L-histidine:2-amino-2-deoxy-D-gluconate Nπ-phosphotransferase | ||||||||
| Comments: | This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9 (phosphoenolpyruvate—protein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||
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| EC | 4.3.1.9 | ||||||||
| Accepted name: | glucosaminate ammonia-lyase | ||||||||
| Reaction: | 2-amino-2-deoxy-D-gluconate = 2-dehydro-3-deoxy-D-gluconate + NH3 (overall reaction) (1a) 2-amino-2-deoxy-D-gluconate = (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate + H2O (1b) (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate = (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate (spontaneous) (1c) (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O = 2-dehydro-3-deoxy-D-gluconate + NH3 (spontaneous) |
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| Glossary: | 2-amino-2-deoxy-D-gluconate = glucosaminate | ||||||||
| Other name(s): | glucosaminic dehydrase; D-glucosaminate dehydratase; D-glucosaminic acid dehydrase; aminodeoxygluconate dehydratase; 2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating); aminodeoxygluconate ammonia-lyase; 2-amino-2-deoxy-D-gluconate ammonia-lyase; D-glucosaminate ammonia-lyase; D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming) | ||||||||
| Systematic name: | 2-amino-2-deoxy-D-gluconate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming) | ||||||||
| Comments: | Contains pyridoxal phosphate. The enzyme releases an unstable enamine product that tautomerizes to an imine form, which undergoes spontaneous hydrolytic deamination to form the final product. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37290-91-8 | ||||||||
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| EC | 4.3.1.29 | ||||||||
| Accepted name: | D-glucosaminate-6-phosphate ammonia-lyase | ||||||||
| Reaction: | 2-amino-2-deoxy-D-gluconate 6-phosphate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + NH3 | ||||||||
| Other name(s): | DgaE; 6-phospho-D-glucosaminate ammonia-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming) | ||||||||
| Systematic name: | 2-amino-2-deoxy-D-gluconate 6-phosphate ammonia-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming) | ||||||||
| Comments: | The enzyme, from the bacterium Salmonella typhimurium, is involved in the degradation pathway of 2-amino-2-deoxy-D-gluconate. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||
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