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Your query returned 2 entries. Printable version
EC | 1.1.1.110 | ||||||||||
Accepted name: | aromatic 2-oxoacid reductase | ||||||||||
Reaction: | (1) (R)-3-(phenyl)lactate + NAD+ = 3-phenylpyruvate + NADH + H+ (2) (R)-3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH + H+ (3) (R)-(indol-3-yl)lactate + NAD+ = (indol-3-yl)pyruvate + NADH + H+ |
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Glossary: | 3-phenylpyruvate = 2-oxo-3-phenylpropanoate | ||||||||||
Other name(s): | (R)-aromatic lactate dehydrogenase; (R)-4-hydroxyphenyllactate dehydrogenase; indolelactate:NAD+ oxidoreductase; indolelactate dehydrogenase; fldH (gene name); (indol-3-yl)lactate:NAD+ oxidoreductase | ||||||||||
Systematic name: | aromatic 2-oxoacid:NAD+ oxidoreductase | ||||||||||
Comments: | The enzymes from anaerobic bacteria such as Clostridium sporogenes participate in the fermentation pathways of L-phenylalanine, L-tyrosine and L-tryptophan. The enzyme from the yeast Candida maltosa has similar activity, but, unlike the bacterial enzyme, requires Mn2+ and can also use NADPH with lower activity. | ||||||||||
Links to other databases: | BRENDA, EXPASY, GTD, KEGG, MetaCyc, CAS registry number: 37250-41-2 | ||||||||||
References: |
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EC | 2.1.1.281 | ||||||||||
Accepted name: | phenylpyruvate C3-methyltransferase | ||||||||||
Reaction: | S-adenosyl-L-methionine + 3-phenylpyruvate = S-adenosyl-L-homocysteine + (3S)-2-oxo-3-phenylbutanoate | ||||||||||
Glossary: | 3-phenylpyruvate = 2-oxo-3-phenylpropanoate (3S)-2-oxo-3-phenylbutanoate = (3S)-β-methyl-phenylpyruvate |
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Other name(s): | phenylpyruvate Cβ-methyltransferase; phenylpyruvate methyltransferase; mppJ (gene name) | ||||||||||
Systematic name: | S-adenosyl-L-methionine:2-oxo-3-phenylpropanoate C3-methyltransferase | ||||||||||
Comments: | The enzyme from the bacterium Streptomyces hygroscopicus NRRL3085 is involved in synthesis of the nonproteinogenic amino acid (2S,3S)-β-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||
References: |
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