EC |
1.2.1.60 |
Accepted name: |
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase |
Reaction: |
5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + 2 H+ |
Other name(s): |
carboxymethylhydroxymuconic semialdehyde dehydrogenase |
Systematic name: |
5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase |
Comments: |
Involved in the tyrosine degradation pathway in Arthrobacter sp. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 63241-20-3 |
References: |
1. |
Blakley, E.R. The catabolism of L-tyrosine by an Arthrobacter sp. Can. J. Microbiol. 23 (1977) 1128–1139. [PMID: 20216] |
2. |
Alonso, J.M. and Garrido-Pertierra, A. Carboxymethylhydroxymuconic semialdehyde dehydrogenase in the 4-hydroxyphenylacetate catabolic pathway of Escherichia coli. Biochim. Biophys. Acta 719 (1982) 165–167. [DOI] [PMID: 6756482] |
3. |
Cooper, R.A. and Skinner, M.A. Catabolism of 3- and 4-hydroxyphenylacetate by the 3,4-dihydroxyphenylacetate pathway in Escherichia coli. J. Bacteriol. 143 (1980) 302–306. [PMID: 6995433] |
4. |
Garrido-Pertierra, A. and Cooper, R.A. Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate pathway of Escherichia coli. Eur. J. Biochem. 117 (1981) 581–584. [DOI] [PMID: 7026235] |
|
[EC 1.2.1.60 created 2000] |
|
|
|
|
EC |
5.3.3.10 |
Accepted name: |
5-carboxymethyl-2-hydroxymuconate Δ-isomerase |
Reaction: |
5-carboxymethyl-2-hydroxymuconate = (3E,5R)-5-carboxy-2-oxohept-3-enedioate |
Glossary: |
5-carboxymethyl-2-hydroxymuconate = (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate |
Other name(s): |
CHM isomerase; 5-carboxymethyl-2-hydroxymuconic acid isomerase |
Systematic name: |
5-carboxymethyl-2-hydroxymuconate Δ2,Δ4-2-oxo,Δ3-isomerase |
Comments: |
Part of the homoprotocatechuate degradation pathway in Escherichia coli C. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 79079-05-3 |
References: |
1. |
Garrido-Pertierra, A. and Cooper, R.A. Identification and purification of distinct isomerase and decarboxylase enzymes involved in the 4-hydroxyphenylacetate pathway of Escherichia coli. Eur. J. Biochem. 117 (1981) 581–584. [DOI] [PMID: 7026235] |
2. |
Johnson, W.H., Jr., Hajipour, G. and Whitman, C.P. Stereochemical studies of 5-(carboxymethyl)-2-hydroxymuconate isomerase and 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dioate decarboxylase from Escherichia coli C: mechanistic and evolutionary implications. J. Am. Chem. Soc. 117 (1995) 8719–8726. |
|
[EC 5.3.3.10 created 1984] |
|
|
|
|