EC |
2.7.1.92 |
Accepted name: |
5-dehydro-2-deoxygluconokinase |
Reaction: |
ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate |
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For diagram of inositol catabolism, click here |
Other name(s): |
5-keto-2-deoxygluconokinase; 5-keto-2-deoxyglucono kinase (phosphorylating); DKH kinase |
Systematic name: |
ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 62213-35-8 |
References: |
1. |
Anderson, W.A. and Magasanik, B. The pathway of myo-inositol degradation in Aerobacter aerogenes. Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates. J. Biol. Chem. 246 (1971) 5662–5675. [PMID: 4328832] |
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[EC 2.7.1.92 created 1976] |
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EC |
4.1.2.29 |
Accepted name: |
5-dehydro-2-deoxyphosphogluconate aldolase |
Reaction: |
5-dehydro-2-deoxy-D-gluconate 6-phosphate = glycerone phosphate + malonate semialdehyde |
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For diagram of inositol catabolism, click here |
Glossary: |
glycerone phosphate = dihydroxyacetone phosphate = 3-hydroxy-2-oxopropyl phosphate |
Other name(s): |
phospho-5-keto-2-deoxygluconate aldolase; 5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase |
Systematic name: |
5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (glycerone-phosphate-forming) |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 62213-25-6 |
References: |
1. |
Anderson, W.A. and Magasanik, B. The pathway of myo-inositol degradation in Aerobacter aerogenes. Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates. J. Biol. Chem. 246 (1971) 5662–5675. [PMID: 4328832] |
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[EC 4.1.2.29 created 1976] |
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EC |
5.3.1.30 |
Accepted name: |
5-deoxy-glucuronate isomerase |
Reaction: |
5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate |
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For diagram of inositol catabolism, click here |
Glossary: |
5-dehydro-2-deoxy-D-gluconate = 2-deoxy-D-threo-hex-5-ulosonic acid
5-deoxy-D-glucuronate = 5-deoxy-D-xylo-hexuronic acid
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Other name(s): |
5DG isomerase; IolB |
Systematic name: |
5-deoxy-D-glucuronate aldose-ketose-isomerase |
Comments: |
The enzyme, found in the bacterium Bacillus subtilis, is part of a myo-inositol degradation pathway leading to acetyl-CoA. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Yoshida, K., Yamaguchi, M., Morinaga, T., Kinehara, M., Ikeuchi, M., Ashida, H. and Fujita, Y. myo-Inositol catabolism in Bacillus subtilis. J. Biol. Chem. 283 (2008) 10415–10424. [DOI] [PMID: 18310071] |
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[EC 5.3.1.30 created 2014] |
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