The Enzyme Database

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EC 3.5.2.14     
Accepted name: N-methylhydantoinase (ATP-hydrolysing)
Reaction: ATP + N-methylhydantoin + 2 H2O = ADP + phosphate + N-carbamoylsarcosine
For diagram of creatine biosynthesis, click here
Glossary: N-methylhydantoin = N-methylimidazolidine-2,4-dione
Other name(s): N-methylhydantoin amidohydrolase; methylhydantoin amidase; N-methylhydantoin hydrolase; N-methylhydantoinase; N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing)
Systematic name: N-methylhydantoin amidohydrolase (ATP-hydrolysing)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 100785-00-0
References:
1.  Kim, J.M., Shimizu, S. and Yamada, H. Amidohydrolysis of N-methylhydantoin coupled with ATP hydrolysis. Biochem. Biophys. Res. Commun. 142 (1987) 1006–1012. [DOI] [PMID: 3827889]
[EC 3.5.2.14 created 1989]
 
 
EC 3.5.4.21     
Accepted name: creatinine deaminase
Reaction: creatinine + H2O = N-methylhydantoin + NH3
For diagram of creatine biosynthesis, click here
Glossary: N-methylhydantoin = N-methylimidazolidine-2,4-dione
Other name(s): creatinine hydrolase; creatinine desiminase
Systematic name: creatinine iminohydrolase
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37289-15-9
References:
1.  Szulmajster, J. Bacterial degradation of creatinine. II. Creatinine desimidase. Biochim. Biophys. Acta 30 (1958) 154–163. [DOI] [PMID: 13584408]
[EC 3.5.4.21 created 1972]
 
 


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