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Your query returned 1 entry. Printable version
EC | 2.4.1.327 | ||
Accepted name: | aclacinomycin-T 2-deoxy-L-fucose transferase | ||
Reaction: | dTDP-2-deoxy-β-L-fucose + aclacinomycin T = dTDP + aclacinomycin S | ||
For diagram of aclacinomycin A and Y biosynthesis, click here | |||
Glossary: | idarubicin = (7S,9S)-9-acetyl-7-(3-amino-2,3,6-trideoxy-β-L-lyxo-hexosyloxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione aclacinomycin S = 7-O-(2-deoxy-α-L-fucosyl-(1→4)-rhodosaminyl)aklavinone aclacinomycin T = 7-O-(α-L-rhodosaminyl)aklavinone |
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Other name(s): | AknK | ||
Systematic name: | dTDP-2-deoxy-β-L-fucose:7-(α-L-rhodosaminyl)aklavinone 2-deoxy-α-L-fucosyltransferase | ||
Comments: | The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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