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Your query returned 1 entry. Printable version
EC | 2.6.1.97 | ||||
Accepted name: | archaeosine synthase | ||||
Reaction: | L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA | ||||
Glossary: | 7-cyano-7-carbaguanine = preQ0 = 7-cyano-7-deazaguanine archaeine = 7-deaza-7-carbamidoylguanine = base G* archaeosine = G* = 7-amidino-7-deazaguanosine |
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Other name(s): | ArcS; TgtA2; MJ1022 (gene name); glutamine:preQ0-tRNA amidinotransferase (incorrect) | ||||
Systematic name: | L-glutamine:7-cyano-7-carbaguanine aminotransferase | ||||
Comments: | In Euryarchaeota the reaction is catalysed by ArcS [1,2]. In Crenarchaeota, which do not have an ArcS homologue, the reaction is catalysed either by a homologue of EC 6.3.4.20, 7-cyano-7-deazaguanine synthase that includes a glutaminase domain (cf. EC 3.5.1.2), or by a homologue of EC 1.7.1.13, preQ1 synthase [2]. The enzyme from the Euryarchaeon Methanocaldococcus jannaschii can also use arginine and ammonium as amino donors. | ||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||
References: |
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