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Your query returned 3 entries. Printable version
EC | 1.21.3.7 | ||||||||
Accepted name: | tetrahydrocannabinolic acid synthase | ||||||||
Reaction: | cannabigerolate + O2 = Δ9-tetrahydrocannabinolate + H2O2 | ||||||||
For diagram of cannabinoid biosynthesis, click here | |||||||||
Glossary: | Δ9-tetrahydrocannabinolate = Δ9-THCA = (6aR,10aR)-1-hydroxy-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromene-2-carboxylate cannabigerolate = CBGA = 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxy-6-pentylbenzoate cannabinerolate = 3-[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxy-6-pentylbenzoate |
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Other name(s): | THCA synthase; Δ1-tetrahydrocannabinolic acid synthase | ||||||||
Systematic name: | cannabigerolate:oxygen oxidoreductase (cyclizing, Δ9-tetrahydrocannabinolate-forming) | ||||||||
Comments: | A flavoprotein (FAD). The cofactor is covalently bound. Part of the cannabinoids biosynthetic pathway in the plant Cannabis sativa. The enzyme can also convert cannabinerolate (the (Z)-isomer of cannabigerolate) to Δ9-THCA with lower efficiency. Whereas the product was originally called Δ1-tetrahydrocannabinolate, the recommended name according to systematic peripheral numbering is Δ9-tetrahydrocannabinolate. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||
References: |
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EC | 1.21.3.8 | ||||||||
Accepted name: | cannabidiolic acid synthase | ||||||||
Reaction: | cannabigerolate + O2 = cannabidiolate + H2O2 | ||||||||
For diagram of cannabinoid biosynthesis, click here | |||||||||
Glossary: | cannabigerolate = CBGA = 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxy-6-pentylbenzoate cannabidiolate = 2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylbenzoate |
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Other name(s): | CBDA synthase | ||||||||
Systematic name: | cannabigerolate:oxygen oxidoreductase (cyclizing, cannabidiolate-forming) | ||||||||
Comments: | Binds FAD covalently. Part of the cannabinoids biosynthetic pathway of the plant Cannabis sativa. The enzyme can also convert cannabinerolate to cannabidiolate with lower efficiency. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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EC | 2.5.1.102 | ||||||||
Accepted name: | geranyl-pyrophosphate—olivetolic acid geranyltransferase | ||||||||
Reaction: | geranyl diphosphate + 2,4-dihydroxy-6-pentylbenzoate = diphosphate + cannabigerolate | ||||||||
For diagram of cannabinoid biosynthesis, click here | |||||||||
Glossary: | 2,4-dihydroxy-6-pentylbenzoate = olivetolate cannabigerolate = CBGA = 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxy-6-pentylbenzoate cannabinerolate = 3-[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]-2,4-dihydroxy-6-pentylbenzoate |
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Other name(s): | GOT (ambiguous) | ||||||||
Systematic name: | geranyl-diphosphate:olivetolate geranyltransferase | ||||||||
Comments: | Part of the cannabinoids biosynthetic pathway of the plant Cannabis sativa. The enzyme can also use neryl diphosphate as substrate, forming cannabinerolate. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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