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Your query returned 1 entry. Printable version
EC | 1.14.19.12 | ||
Accepted name: | acyl-lipid ω-(9-4) desaturase | ||
Reaction: | (1) linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = pinolenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O (2) α-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = coniferonoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O |
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Glossary: | taxoleate = (5Z,9Z)-octadeca-5,9-dienoate pinolenoate = (5Z,9Z,12Z)-octadeca-5,9,12-trienoate coniferonate = (5Z,9Z,12Z,15Z)-octadeca-5,9,12,15-tetraenoate |
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Other name(s): | acyl-lipid ω-13 desaturase; acyl-lipid 7-desaturase (ambiguous) | ||
Systematic name: | acyl-[glycerolipid],ferrocytochrome b5:oxygen oxidoreductase [ω(9-4),ω(9-5) cis-dehydrogenating] | ||
Comments: | The enzyme, characterized from the green alga Chlamydomonas reinhardtii, is a front-end desaturase that introduces a cis double bond in ω9 unsaturated C18 or C20 fatty acids incorporated into lipids, at a position 4 carbon atoms from the existing ω9 bond, towards the carboxy end of the fatty acid (at the ω13 position). When acting on 20:2Δ(11,14) and 20:3Δ(11,14,17) substrates it introduces the new double bond between carbons 7 and 8. The enzyme contains a cytochrome b5 domain that acts as the direct electron donor for the active site of the desaturase. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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