The Enzyme Database

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EC 2.3.1.210     
Accepted name: dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase
Reaction: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-α-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-α-D-galactose
For diagram of dTDP-Fuc3NAc and dTDP-Fuc4NAc biosynthesis, click here
Glossary: dTDP-4-amino-4,6-dideoxy-α-D-galactose = dTDP-α-D-fucosamine
Other name(s): TDP-fucosamine acetyltransferase; WecD; RffC
Systematic name: acetyl-CoA:dTDP-4-amino-4,6-dideoxy-α-D-galactose N-acetyltransferase
Comments: The product, TDP-4-acetamido-4,6-dideoxy-D-galactose, is utilized in the biosynthesis of enterobacterial common antigen (ECA).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
References:
1.  Hung, M.N., Rangarajan, E., Munger, C., Nadeau, G., Sulea, T. and Matte, A. Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis. J. Bacteriol. 188 (2006) 5606–5617. [DOI] [PMID: 16855251]
[EC 2.3.1.210 created 2012]
 
 
EC 2.6.1.59     
Accepted name: dTDP-4-amino-4,6-dideoxygalactose transaminase
Reaction: dTDP-4-amino-4,6-dideoxy-α-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-α-D-galactose + L-glutamate
For diagram of dTDP-Fuc3NAc, dTDP-Fuc4NAc and dTDP-Fuc3NMe2 biosynthesis, click here
Glossary: dTDP-4-dehydro-6-deoxy-α-D-galactose = dTDP-4-dehydro-6-deoxy-α-D-glucose
Other name(s): thymidine diphosphoaminodideoxygalactose aminotransferase; thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase; WecE; dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase; dTDP-4,6-dideoxy-α-D-galactose:2-oxoglutarate aminotransferase
Systematic name: dTDP-4-amino-4,6-dideoxy-α-D-galactose:2-oxoglutarate aminotransferase
Comments: A pyridoxal-phosphate protein.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 72560-97-5
References:
1.  Ohashi, H., Matsuhashi, M. and Matsuhashi, S. Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis. J. Biol. Chem. 246 (1971) 2325–2330. [PMID: 4928644]
2.  Hwang, B.Y., Lee, H.J., Yang, Y.H., Joo, H.S. and Kim, B.G. Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12. Chem. Biol. 11 (2004) 915–925. [DOI] [PMID: 15271350]
[EC 2.6.1.59 created 1978]
 
 


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