EC |
2.3.1.210 |
Accepted name: |
dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase |
Reaction: |
acetyl-CoA + dTDP-4-amino-4,6-dideoxy-α-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-α-D-galactose |
|
For diagram of dTDP-Fuc3NAc and dTDP-Fuc4NAc biosynthesis, click here |
Glossary: |
dTDP-4-amino-4,6-dideoxy-α-D-galactose = dTDP-α-D-fucosamine |
Other name(s): |
TDP-fucosamine acetyltransferase; WecD; RffC |
Systematic name: |
acetyl-CoA:dTDP-4-amino-4,6-dideoxy-α-D-galactose N-acetyltransferase |
Comments: |
The product, TDP-4-acetamido-4,6-dideoxy-D-galactose, is utilized in the biosynthesis of enterobacterial common antigen (ECA). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
References: |
1. |
Hung, M.N., Rangarajan, E., Munger, C., Nadeau, G., Sulea, T. and Matte, A. Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis. J. Bacteriol. 188 (2006) 5606–5617. [DOI] [PMID: 16855251] |
|
[EC 2.3.1.210 created 2012] |
|
|
|
|
EC |
2.6.1.59 |
Accepted name: |
dTDP-4-amino-4,6-dideoxygalactose transaminase |
Reaction: |
dTDP-4-amino-4,6-dideoxy-α-D-galactose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-α-D-galactose + L-glutamate |
|
For diagram of dTDP-Fuc3NAc, dTDP-Fuc4NAc and dTDP-Fuc3NMe2 biosynthesis, click here |
Glossary: |
dTDP-4-dehydro-6-deoxy-α-D-galactose = dTDP-4-dehydro-6-deoxy-α-D-glucose
|
Other name(s): |
thymidine diphosphoaminodideoxygalactose aminotransferase; thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase; WecE; dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase; dTDP-4,6-dideoxy-α-D-galactose:2-oxoglutarate aminotransferase |
Systematic name: |
dTDP-4-amino-4,6-dideoxy-α-D-galactose:2-oxoglutarate aminotransferase |
Comments: |
A pyridoxal-phosphate protein. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 72560-97-5 |
References: |
1. |
Ohashi, H., Matsuhashi, M. and Matsuhashi, S. Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis. J. Biol. Chem. 246 (1971) 2325–2330. [PMID: 4928644] |
2. |
Hwang, B.Y., Lee, H.J., Yang, Y.H., Joo, H.S. and Kim, B.G. Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12. Chem. Biol. 11 (2004) 915–925. [DOI] [PMID: 15271350] |
|
[EC 2.6.1.59 created 1978] |
|
|
|
|