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Your query returned 2 entries. Printable version
EC | 2.1.1.338 | ||
Accepted name: | desmethylxanthohumol 6′-O-methyltransferase | ||
Reaction: | S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol | ||
For diagram of xanthohumol biosynthesis, click here | |||
Glossary: | desmethylxanthohumol = 2′,4,4′,6′-tetrahydroxy-3-prenylchalcone = (2E)-3-(4-hydroxyphenyl)-1-[2,4,6-trihydroxy-3-(3-methylbut-2-en-1-yl)phenyl]prop-2-en-1-one xanthohumol = 2′,4,4′-trihydroxy-6′-methoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one |
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Other name(s): | OMT1 (ambiguous) | ||
Systematic name: | S-adenosyl-L-methionine:desmethylxanthohumol 6′-O-methyltransferase | ||
Comments: | Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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EC | 2.1.1.339 | ||
Accepted name: | xanthohumol 4-O-methyltransferase | ||
Reaction: | S-adenosyl-L-methionine + xanthohumol = S-adenosyl-L-homocysteine + 4-O-methylxanthohumol | ||
For diagram of xanthohumol biosynthesis, click here | |||
Glossary: | xanthohumol = 2′,4,4′-trihydroxy-6′-methoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one 4-O-methylxanthohumol =2′,4′-dihydroxy-4,6′-dimethoxy-3-prenylchalcone = (2E)-1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one |
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Other name(s): | OMT2 (ambiguous); S-adenosyl-L-methionine:xanthohumol 4′-O-methyltransferase (incorrect); xanthohumol 4′-O-methyltransferase (incorrect) | ||
Systematic name: | S-adenosyl-L-methionine:xanthohumol 4-O-methyltransferase | ||
Comments: | The enzyme from hops (Humulus lupulus) has a broad substrate specificity. The best substrates in vitro are resveratrol, desmethylxanthohumol, naringenin chalcone and isoliquiritigenin. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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