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Your query returned 3 entries. 
Printable version
| EC | 2.3.1.156 | ||||||
| Accepted name: | phloroisovalerophenone synthase | ||||||
| Reaction: | (1) isovaleryl-CoA + 3 malonyl-CoA = 4 CoA + 3 CO2 + phlorisovalerophenone (2) isobutyryl-CoA + 3 malonyl-CoA = 4 CoA + 3 CO2 + phlorisobutyrophenone |
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| For diagram of polyketides biosynthesis, click here | |||||||
| Glossary: | phlorisobutyrophenone = 2-methyl-1-(2,4,6-trihydroxyphenyl)propan-1-one phlorisovalerophenone = 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one |
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| Other name(s): | valerophenone synthase; 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase; acylphloroglucinol synthase; isovaleryl-CoA:malonyl-CoA acyltransferase | ||||||
| Systematic name: | acyl-CoA:malonyl-CoA acyltransferase | ||||||
| Comments: | Closely related to EC 2.3.1.74, naringenin-chalcone synthase. Also acts on isobutyryl-CoA as substrate to give phlorisobutyrophenone. The products are intermediates in the biosynthesis of the bitter acids in hops (Humulus lupulus) and glucosides in strawberry (Fragaria X ananassa). It is also able to generate naringenin chalcone from 4-coumaroyl-CoA. | ||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
| References: |
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| EC | 2.4.1.358 | ||||||
| Accepted name: | acylphloroglucinol glucosyltransferase | ||||||
| Reaction: | UDP-α-D-glucose + 2-acylphloroglucinol = UDP + 2-acylphloroglucinol 1-O-β-D-glucoside | ||||||
| Glossary: | phlorisobutyrophenone = 2-methyl-1-(2,4,6-trihydroxyphenyl)propan-1-one phlorisovalerophenone = 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one |
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| Other name(s): | UGT71K3 | ||||||
| Systematic name: | UDP-α-D-glucose:2-acylphloroglucinol 1-O-β-glucosyltransferase | ||||||
| Comments: | Isolated from strawberries (Fragaria X ananassa). Acts best on phloroisovalerophenone and phlorobutyrophenone but will also glycosylate many other phenolic compounds. A minor product of the reaction is the 5-O-β-D-glucoside. | ||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
| References: |
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| EC | 2.5.1.136 | ||||||
| Accepted name: | 2-acylphloroglucinol 4-prenyltransferase | ||||||
| Reaction: | prenyl diphosphate + a 2-acylphloroglucinol = diphosphate + a 2-acyl-4-prenylphloroglucinol | ||||||
| Glossary: | naringenin chalcone = 2′,4,4′,6′-tetrahydroxychalcone = 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one phlorisovalerophenone = 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one |
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| Other name(s): | PT-1 (gene name); PT1L (gene name); aromatic prenyltransferase (ambiguous); dimethylallyl-diphosphate:2-acylphloroglucinol 4-dimethylallyltransferase | ||||||
| Systematic name: | prenyl-diphosphate:2-acylphloroglucinol 4-prenyltransferase | ||||||
| Comments: | The enzyme, characterized from hop (Humulus lupulus), acts on phlorisovalerophenone, phlormethylbutanophenone, and phlorisobutanophenone during the synthesis of bitter acids. It also acts with much lower activity on naringenin chalcone. Forms a complex with EC 2.5.1.137, 2-acyl-4-prenylphloroglucinol 6-prenyltransferase, which catalyses additional prenylation reactions. Requires Mg2+. | ||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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