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Your query returned 3 entries. Printable version
EC | 1.3.1.117 | ||||||||
Accepted name: | hydroxycinnamoyl-CoA reductase | ||||||||
Reaction: | (1) dihydro-4-coumaroyl-CoA + NADP+ = trans-4-coumaroyl-CoA + NADPH + H+ (2) dihydroferuloyl-CoA + NADP+ = trans-feruloyl-CoA + NADPH + H+ |
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For diagram of phloretin biosynthesis, click here | |||||||||
Glossary: | trans-4-coumaroyl-CoA = (E)-3-(4-hydroxyphenyl)prop-2-enoyl-CoA trans-feruloyl-CoA = (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl-CoA dihydro-4-coumaroyl-CoA = 3-(4-hydroxyphenyl)propanoyl-CoA dihydroferuloyl-CoA = 3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA |
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Other name(s): | MdHCDBR; hydroxycinnamoyl-CoA double bond reductase | ||||||||
Systematic name: | dihydro-4-coumaroyl-CoA:NADP+ 2,3-oxidoreductase | ||||||||
Comments: | Isolated from Malus X domestica (apple). Involved in dihydrochalcone biosynthesis. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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EC | 1.14.11.61 | ||||||||
Accepted name: | feruloyl-CoA 6-hydroxylase | ||||||||
Reaction: | trans-feruloyl-CoA + 2-oxoglutarate + O2 = trans-6-hydroxyferuloyl-CoA + succinate + CO2 | ||||||||
Glossary: | trans-feruloyl-CoA = 4-hydroxy-3-methoxycinnamoyl-CoA = (E)-3-(4-hydroxy-3-methoxyphenyl)propenoyl-CoA | ||||||||
Systematic name: | feruloyl-CoA,2-oxoglutarate:oxygen oxidoreductase (6-hydroxylating) | ||||||||
Comments: | Requires iron(II) and ascorbate. The product spontaneously undergoes trans-cis isomerization and lactonization to form scopoletin, liberating CoA in the process. The enzymes from the plants Ruta graveolens and Ipomoea batatas also act on trans-4-coumaroyl-CoA. cf. EC 1.14.11.62, trans-4-coumaroyl-CoA 2-hydroxylase. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||
References: |
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EC | 1.14.11.62 | ||||||||
Accepted name: | trans-4-coumaroyl-CoA 2-hydroxylase | ||||||||
Reaction: | trans-4-coumaroyl-CoA + 2-oxoglutarate + O2 = 2,4-dihydroxycinnamoyl-CoA + succinate + CO2 | ||||||||
Glossary: | trans-4-coumaroyl-CoA = (2E)-3-(4-hydroxyphenyl)prop-2-enoyl-CoA 2,4-dihydroxycinnamoyl-CoA = (2E)-3-(2,4-dihydroxyphenyl)prop-2-enoyl-CoA umbelliferone = 7-hydroxycoumarin |
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Other name(s): | Diox4 (gene name); C2′H (gene name) | ||||||||
Systematic name: | (2E)-3-(4-hydroxyphenyl)prop-2-enoyl-CoA,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) | ||||||||
Comments: | Requires iron(II) and ascorbate. The product spontaneously undergoes trans-cis isomerization followed by lactonization and cyclization, liberating CoA and forming umbelliferone. The enzymes from the plants Ruta graveolens and Ipomoea batatas also act on trans-feruloyl-CoA (cf. EC 1.14.11.61, feruloyl-CoA 6-hydroxylase). | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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