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Your query returned 4 entries. Printable version
EC | 1.1.1.353 | ||||||||
Accepted name: | versiconal hemiacetal acetate reductase | ||||||||
Reaction: | (1) versicolorone + NADP+ = 1′-hydroxyversicolorone + NADPH + H+ (2) versiconol acetate + NADP+ = versiconal hemiacetal acetate + NADPH + H+ (3) versiconol + NADP+ = versiconal + NADPH + H+ |
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Glossary: | 1′-hydroxyversicolorone = (2S,3S)-2,4,6,8-tetrahydroxy-3-(3-oxobutyl)anthra[2,3-b]furan-5,10-dione versiconal = (2S,3S)-2,4,6,8-tetrahydroxy-3-(2-hydroxyethyl)anthra[2,3-b]furan-5,10-dione versiconal hemiacetal acetate = 2-[(2S,3S)-2,4,6,8-tetrahydroxy-5,10-dioxo-5,10-dihydroanthra[2,3-b]furan-3-yl]ethyl acetate versiconol = 1,3,6,8-tetrahydroxy-3-[(2S)-1,4-dihydroxybutan-2-yl]anthracene-5,10-dione versiconol acetate = (3S)-4-hydroxy-3-[1,3,6,8-tetrahydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl]butyl acetate versicolorone = 1,3,6,8-tetrahydroxy-2-[(2S)-1-hydroxy-5-oxohexan-2-yl]anthracene-5,10-dione |
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Other name(s): | VHA reductase; VHA reductase I; VHA reductase II; vrdA (gene name) | ||||||||
Systematic name: | versiconol-acetate:NADP+ oxidoreductase | ||||||||
Comments: | Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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EC | 3.1.1.94 | ||||||||
Accepted name: | versiconal hemiacetal acetate esterase | ||||||||
Reaction: | (1) versiconal hemiacetal acetate + H2O = versiconal + acetate (2) versiconol acetate + H2O = versiconol + acetate |
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For diagram of aflatoxin biosynthesis (part 2), click here | |||||||||
Glossary: | versiconal = (2S,3S)-2,4,6,8-tetrahydroxy-3-(2-hydroxyethyl)anthra[2,3-b]furan-5,10-dione versiconal hemiacetal acetate = 2-[(2S,3S)-2,4,6,8-tetrahydroxy-5,10-dioxo-5,10-dihydroanthra[2,3-b]furan-3-yl]ethyl acetate versiconol = 1,3,6,8-tetrahydroxy-3-[(2S)-1,4-dihydroxybutan-2-yl]anthracene-5,10-dione versiconol acetate = (3S)-4-hydroxy-3-[1,3,6,8-tetrahydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl]butyl acetate |
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Other name(s): | VHA esterase | ||||||||
Systematic name: | versiconal-hemiacetal-acetate O-acetylhydrolase | ||||||||
Comments: | Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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EC | 4.2.1.142 | ||||||||
Accepted name: | 5′-oxoaverantin cyclase | ||||||||
Reaction: | 5′-oxoaverantin = (1′S,5′S)-averufin + H2O | ||||||||
For diagram of aflatoxin biosynthesis (part 1), click here | |||||||||
Glossary: | 5′-oxoaverantin = 1,3,6,8-tetrahydroxy-2-[(1S)-1-hydroxy-5-oxohexyl]anthracene-9,10-dione averufin = 7,9,11-trihydroxy-2-methyl-3,4,5,6-tetrahydro-2,6-epoxy-2H-anthra[2,3-b]oxocin-8,13-dione |
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Other name(s): | OAVN cyclase; 5′-oxoaverantin hydro-lyase [(2′S,5′S)-averufin forming] | ||||||||
Systematic name: | 5′-oxoaverantin hydro-lyase [(1′S,5′S)-averufin-forming] | ||||||||
Comments: | Isolated from the aflatoxin-producing mold Aspergillus parasiticus. The enzyme also catalyses the conversion of versiconal to versicolorin B (EC 4.2.1.143, versicolorin B synthase). Involved in aflatoxin biosynthesis. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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EC | 4.2.1.143 | ||||||||
Accepted name: | versicolorin B synthase | ||||||||
Reaction: | versiconal = versicolorin B + H2O | ||||||||
For diagram of aflatoxin biosynthesis (part 2), click here | |||||||||
Glossary: | versiconal = (2S,3S)-2,4,6,8-tetrahydroxy-3-(2-hydroxyethyl)anthra[2,3-b]furan-5,10-dione versicolorin B = (3aR,12bS)-8,10,12-trihydroxy-1,2,3a,12b-tetrahydroanthra[2,3-b]furo[3,2-d]furan-6,11-dione |
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Other name(s): | versiconal cyclase; VBS | ||||||||
Systematic name: | versiconal hydro-lyase (versicolorin-B-forming) | ||||||||
Comments: | Isolated from the aflatoxin-producing mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. | ||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||
References: |
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