EC |
1.1.1.151 |
Accepted name: |
21-hydroxysteroid dehydrogenase (NADP+) |
Reaction: |
pregnan-21-ol + NADP+ = pregnan-21-al + NADPH + H+ |
Other name(s): |
21-hydroxy steroid dehydrogenase; 21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase; 21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate); NADP-21-hydroxysteroid dehydrogenase; 21-hydroxysteroid dehydrogenase (NADP) |
Systematic name: |
21-hydroxysteroid:NADP+ 21-oxidoreductase |
Comments: |
Acts on a number of 21-hydroxycorticosteroids. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 37250-76-3 |
References: |
1. |
Monder, C. and White, A. The 21-hydroxysteroid dehydrogenases of liver. A nicotinamide adenine dinucleotide phosphate dehydrogenase and two nicotinamide adenine dinucleotide dehydrogenases. J. Biol. Chem. 240 (1965) 71–77. [PMID: 14253469] |
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[EC 1.1.1.151 created 1972] |
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