The Enzyme Database

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Accepted name: hydroxyphenylpyruvate reductase
Reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH + H+
For diagram of 4-hydroxyphenylpyruvate metabolites, click here and for diagram of rosmarinate biosynthesis, click here
Other name(s): HPPR
Systematic name: 4-hydroxyphenyllactate:NAD+ oxidoreductase
Comments: Also acts on 3-(3,4-dihydroxyphenyl)lactate. Involved with EC rosmarinate synthase in the biosynthesis of rosmarinic acid.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 117590-77-9
1.  Petersen, M. and Alfermann, A.W. Two new enzymes of rosmarinic acid biosynthesis from cell cultures of Coleus blumei: hydroxyphenylpyruvate reductase and rosmarinic acid synthase. Z. Naturforsch. C: Biosci. 43 (1988) 501–504.
[EC created 1992]

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