The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 1.1.1.273     
Accepted name: vellosimine dehydrogenase
Reaction: 10-deoxysarpagine + NADP+ = vellosimine + NADPH + H+
For diagram of geissoschizine and sarpagine biosynthesis, click here
Systematic name: 10-deoxysarpagine:NADP+ oxidoreductase
Comments: Also acts on related alkaloids with an endo-aldehyde group as vellosimine (same stereochemistry at C-16) but only slight activity with exo-aldehydes. Detected in many cell suspension cultures of plants from the family Apocynaceae.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 86777-26-6
References:
1.  Pfitzner, A., Krausch, B. and Stöckigt, J. Characteristics of vellosimine reductase, a specific enzyme involved in the biosynthesis of the Rauwolfia alkaloid sarpagine. Tetrahedron 40 (1984) 1691–1699.
[EC 1.1.1.273 created 2002]
 
 


Data © 2001–2017 IUBMB
Web site © 2005–2017 Andrew McDonald