The reaction is catalysed in the reverse direction. This activity is usually associated with butanediol dehydrogenase activity (EC 18.104.22.168 or EC 22.214.171.124). While the butanediol dehydrogenase activity is reversible, diacetyl reductase activity is irreversible. This enzyme has been reported in the yeast Saccharomyces cerevisiae [1,2]. Different from EC 126.96.36.1994, diacetyl reductase [(S)-acetoin forming].
Heidlas, J. and Tressl, R. Purification and characterization of a (R)-2,3-butanediol dehydrogenase from Saccharomyces cerevisiae. Arch. Microbiol.154 (1990) 267–273. [PMID: 2222122]
Gonzalez, E., Fernandez, M.R., Larroy, C., Sola, L., Pericas, M.A., Pares, X. and Biosca, J.A. Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene. J. Biol. Chem.275 (2000) 35876–35885. [DOI] [PMID: 10938079]
[EC 188.8.131.523 created 2010 (EC 184.108.40.206 created 1961, modified 1976, part incorporated 2010)]