The enzyme, which occurs in the bacteria Azotobacter vinelandii and Sphingomonas sp. SKA58, is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC 126.96.36.199, L-rhamnose 1-dehydrogenase, which is specific for NAD+ and EC 188.8.131.527, L-rhamnose 1-dehydrogenase (NADP+).
Watanabe, S., Saimura, M. and Makino, K. Eukaryotic and bacterial gene clusters related to an alternative pathway of nonphosphorylated L-rhamnose metabolism. J. Biol. Chem.283 (2008) 20372–20382. [DOI] [PMID: 18505728]
Watanabe, S. and Makino, K. Novel modified version of nonphosphorylated sugar metabolism – an alternative L-rhamnose pathway of Sphingomonas sp. FEBS J.276 (2009) 1554–1567. [DOI] [PMID: 19187228]