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Accepted name: hydroxyacid-oxoacid transhydrogenase
S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + ( R)-2-hydroxyglutarate
Other name(s): transhydrogenase, hydroxy acid-oxo acid
Systematic name: (
Comments: 4-Hydroxybutanoate and (
R)-2-hydroxyglutarate can also act as donors; 4-oxobutanoate can also act as acceptor.
Links to other databases:
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 117698-31-4
Kaufman, E.E., Nelson, T., Fales, H.M. and Levin, D.M. Isolation and characterization of a hydroxyacid-oxoacid transhydrogenase from rat kidney mitochondria.
J. Biol. Chem. 263 (1988) 16872–16879. [PMID: 3182820]
[EC 220.127.116.11 created 1992]
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