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Your query returned 1 entry. Printable version
EC | 1.14.14.178 | ||||||||||
Accepted name: | steroid 22S-hydroxylase | ||||||||||
Reaction: | (1) a C27-steroid + O2 + [reduced NADPH—hemoprotein reductase] = a (22S)-22-hydroxy-C27-steroid + 2 H2O + [oxidized NADPH—hemoprotein reductase] (2) a C28-steroid + O2 + [reduced NADPH—hemoprotein reductase] = a (22S)-22-hydroxy-C28-steroid + 2 H2O + [oxidized NADPH—hemoprotein reductase] (3) a C29-steroid + O2 + [reduced NADPH—hemoprotein reductase] = a (22S)-22-hydroxy-C29-steroid + 2 H2O + [oxidized NADPH—hemoprotein reductase] |
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Other name(s): | CYP90B1 (gene name); DWF4 (gene name); steroid C-22 hydroxylase | ||||||||||
Systematic name: | steroid,NADPH—hemoprotein reductase:oxygen 22S-oxidoreductase (hydroxylating) | ||||||||||
Comments: | This plant cytochrome P-450 (heme thiolate) enzyme participates in the biosynthesis of brassinosteroids. While in vivo substrates include C28-steroids such as campestanol, campesterol, and 6-oxocampestanol, the enzyme is able to catalyse the C-22 hydroxylation of a variety of C27, C28 and C29 steroids. | ||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||
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