EC |
1.14.14.8 |
Accepted name: |
anthranilate 3-monooxygenase (FAD) |
Reaction: |
anthranilate + FADH2 + O2 = 3-hydroxyanthranilate + FAD + H2O |
Glossary: |
anthranilate = 2-aminobenzoate |
Other name(s): |
anthranilate 3-hydroxylase; anthranilate hydroxylase |
Systematic name: |
anthranilate,FADH2:oxygen oxidoreductase (3-hydroxylating) |
Comments: |
This enzyme, isolated from the bacterium Geobacillus thermodenitrificans, participates in the pathway of tryptophan degradation. The enzyme is part of a system that also includes a bifunctional riboflavin kinase/FMN adenylyltransferase and an FAD reductase, which ensures ample supply of FAD to the monooxygenase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Liu, X., Dong, Y., Li, X., Ren, Y., Li, Y., Wang, W., Wang, L. and Feng, L. Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2. Microbiology 156 (2010) 589–595. [DOI] [PMID: 19942660] |
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[EC 1.14.14.8 created 2010] |
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