EC |
2.1.1.256 |
Accepted name: |
tRNA (guanine6-N2)-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + guanine6 in tRNA = S-adenosyl-L-homocysteine + N2-methylguanine6 in tRNA |
Other name(s): |
methyltransferase Trm14; m2G6 methyltransferase |
Systematic name: |
S-adenosyl-L-methionine:tRNA (guanine6-N2)-methyltransferase |
Comments: |
The enzyme specifically methylates guanine6 at N2 in tRNA. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
References: |
1. |
Menezes, S., Gaston, K.W., Krivos, K.L., Apolinario, E.E., Reich, N.O., Sowers, K.R., Limbach, P.A. and Perona, J.J. Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14. Nucleic Acids Res. 39 (2011) 7641–7655. [DOI] [PMID: 21693558] |
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[EC 2.1.1.256 created 2012] |
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