EC |
2.3.3.6 |
Accepted name: |
2-ethylmalate synthase |
Reaction: |
acetyl-CoA + H2O + 2-oxobutanoate = (R)-2-ethylmalate + CoA |
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For diagram of reaction, click here |
Other name(s): |
(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating); 2-ethylmalate-3-hydroxybutanedioate synthase; propylmalate synthase; propylmalic synthase |
Systematic name: |
acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming) |
Comments: |
Also acts on (R)-2-(n-propyl)-malate. Formerly wrongly included with EC 2.3.3.7 3-ethylmalate synthase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9024-01-5 |
References: |
1. |
Strassman, M. and Ceci, L.N. A study of acetyl-CoA condensation with α-keto acids. Arch. Biochem. Biophys. 119 (1967) 420–428. [PMID: 6052435] |
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[EC 2.3.3.6 created 1983 as EC 4.1.3.33, transferred 2002 to EC 2.3.3.6] |
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