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Your query returned 1 entry. Printable version
EC | 2.5.1.132 | ||||||
Accepted name: | 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase | ||||||
Reaction: | phosphoenolpyruvate + D-mannose 6-phosphate + H2O = 3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate | ||||||
Glossary: | phosphoenolpyruvate = 2-(phosphooxy)-2-propenoate 3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate = Kdn |
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Other name(s): | 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase; 2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid synthase; Kdn 9-P synthase | ||||||
Systematic name: | phosphoenolpyruvate:D-mannose-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase | ||||||
Comments: | The enzyme participates in the biosynthesis of the sialic acid 3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonate (Kdn). The human sialic acid synthase (EC 2.5.1.57) is also able to catalyse the reaction. Kdn is abundant in extracellular glycoconjugates of lower vertebrates such as fish and amphibians, but is also found in the capsular polysaccharides of bacteria that belong to the Bacteroides genus. | ||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
References: |
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