EC |
2.5.1.80 |
Accepted name: |
7-dimethylallyltryptophan synthase |
Reaction: |
prenyl diphosphate + L-tryptophan = diphosphate + 7-prenyl-L-tryptophan |
Glossary: |
prenyl = 3-methylbut-2-en-1-yl |
Other name(s): |
7-DMATS; dimethylallyl-diphosphate:L-tryptophan 7-dimethylallyltransferase |
Systematic name: |
prenyl-diphosphate:L-tryptophan 7-prenyltransferase |
Comments: |
This enzyme is more flexible towards the aromatic substrate than EC 2.5.1.34 (4-dimethylallyltryptophan synthase), but similar to that enzyme, accepts only prenyl diphosphate as the prenyl donor. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Kremer, A. and Li, S.M. Potential of a 7-dimethylallyltryptophan synthase as a tool for production of prenylated indole derivatives. Appl. Microbiol. Biotechnol. 79 (2008) 951–961. [DOI] [PMID: 18481055] |
2. |
Kremer, A., Westrich, L. and Li, S.M. A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization. Microbiology 153 (2007) 3409–3416. [DOI] [PMID: 17906140] |
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[EC 2.5.1.80 created 2010] |
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