EC |
2.6.1.120 |
Accepted name: |
β-alanine—2-oxoglutarate transaminase |
Reaction: |
β-alanine + 2-oxoglutarate = 3-oxopropanoate + L-glutamate |
|
For diagram of pyrimidine catabolism, click here |
Other name(s): |
pydD (gene name); β-alanine aminotransferase |
Systematic name: |
β-alanine:2-oxoglutarate aminotransferase |
Comments: |
The enzyme, found in many Gram-positive bacteria, participates in the reductive degradation of pyrimidines. In eukaryotes this activity is catalysed by EC 2.6.1.19, 4-aminobutyrate—2-oxoglutarate transaminase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Fujimoto, S., Mizutani, N., Mizota, C. and Tamaki, N. The level of β-alanine aminotransferase activity in regenerating and differentiating rat liver. Biochim. Biophys. Acta 882 (1986) 106–112. [DOI] [PMID: 3085724] |
2. |
Yin, J., Wei, Y., Liu, D., Hu, Y., Lu, Q., Ang, E.L., Zhao, H. and Zhang, Y. An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine. J. Biol. Chem. 294 (2019) 15662–15671. [DOI] [PMID: 31455636] |
|
[EC 2.6.1.120 created 2021] |
|
|
|
|