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Your query returned 1 entry. Printable version
EC | 2.8.1.2 | ||||||||||||||||
Accepted name: | 3-mercaptopyruvate sulfurtransferase | ||||||||||||||||
Reaction: | 2-oxo-3-sulfanylpropanoate + reduced thioredoxin = pyruvate + hydrogen sulfide + oxidized thioredoxin (overall reaction) (1a) 2-oxo-3-sulfanylpropanoate + [3-mercaptopyruvate sulfurtransferase]-L-cysteine = pyruvate + [3-mercaptopyruvate sulfurtransferase]-S-sulfanyl-L-cysteine (1b) [3-mercaptopyruvate sulfurtransferase]-S-sulfanyl-L-cysteine + reduced thioredoxin = hydrogen sulfide + [3-mercaptopyruvate sulfurtransferase]-L-cysteine + oxidized thioredoxin |
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Glossary: | 2-oxo-3-sulfanylpropanoate = 3-mercaptopyruvate (deprecated) | ||||||||||||||||
Other name(s): | β-mercaptopyruvate sulfurtransferase; TUM1 (gene name); MPST (gene name); 3-mercaptopyruvate:cyanide sulfurtransferase | ||||||||||||||||
Systematic name: | 2-oxo-3-sulfanylpropanoate:sulfide sulfurtransferase | ||||||||||||||||
Comments: | The enzyme catalyses a transsulfuration reaction from 2-oxo-3-sulfanylpropanoate to an internal cysteine residue. In the presence of a dithiol such as reduced thioredoxin or dihydrolipoate, the sulfanyl sulfur is released as hydrogen sulfide. The enzyme participates in a sulfur relay process that leads to the 2-thiolation of some tRNAs and to protein urmylation by transferring sulfur between the NFS1 cysteine desulfurase (EC 2.8.1.7) and the MOCS3 sulfurtransferase (EC 2.8.1.11). | ||||||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9026-05-5 | ||||||||||||||||
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