EC |
2.8.2.20 |
Accepted name: |
protein-tyrosine sulfotransferase |
Reaction: |
3′-phosphoadenylyl sulfate + protein tyrosine = adenosine 3′,5′-bisphosphate + protein tyrosine-O-sulfate |
Glossary: |
3′-phosphoadenylyl sulfate = PAPS |
Other name(s): |
tyrosylprotein sulfotransferase; 3′-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase |
Systematic name: |
3′-phosphoadenylyl-sulfate:protein-tyrosine O-sulfonotransferase |
Comments: |
The tyrosine residues of some specific proteins of rat pheochromocytoma cells act as acceptors. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 87588-33-8 |
References: |
1. |
Lee, R.W.H. and Huttner, W.B. Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase. J. Biol. Chem. 258 (1983) 11326–11334. [PMID: 6577005] |
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[EC 2.8.2.20 created 1986] |
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