The Enzyme Database

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Accepted name: methylthioadenosine nucleosidase
Reaction: S-methyl-5′-thioadenosine + H2O = S-methyl-5-thio-D-ribose + adenine
For diagram of the methionine-salvage pathway, click here
Other name(s): 5′-methylthioadenosine nucleosidase; MTA nucleosidase; MeSAdo nucleosidase; methylthioadenosine methylthioribohydrolase
Systematic name: S-methyl-5′-thioadenosine adeninehyrolase
Comments: Does not act on S-adenosylhomocysteine. cf. EC adenosylhomocysteine nucleosidase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 50812-28-7
1.  Guranowski, A.B., Chiang, P.K. and Cantoni, G.L. 5′-Methylthioadenosine nucleosidase. Purification and characterization of the enzyme from Lupinus luteus seeds. Eur. J. Biochem. 114 (1981) 293–299. [DOI] [PMID: 6783408]
[EC created 1983, modified 2004]

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