The Enzyme Database

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Accepted name: barrierpepsin
Reaction: Selective cleavage of -Leu6┼Lys- bond in the pheromone α-mating factor
Other name(s): barrier proteinase; Bar proteinase
Comments: A secreted endopeptidase known from baker's yeast (Saccharomyces cerevisiae). In peptidase family A1 (pepsin A family)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, MEROPS, CAS registry number: 152060-38-3
1.  Mackay, V.L., Welch, S.K., Insley, M.Y., Manney, T.R., Holly, J., Saari, G.C. and Parker, M.L. The Saccharomyces cerevisiae BAR1 gene encodes an exported protein with homology to pepsin. Proc. Natl. Acad. Sci. USA 85 (1988) 55–59. [DOI] [PMID: 3124102]
2.  Mackay, V.L., Armstrong, J., Yip, C., Welch, S., Walker, K., Osborn, S., Sheppard, P. and Forstrom, J. Characterization of the bar proteinase, an extracellular enzyme from the yeast Saccharomyces cerevisiae. Adv. Exp. Med. Biol. 306 (1991) 161–172. [PMID: 1812704]
[EC created 1993]

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